Endothelial dysfunction and hyperhomocysteinemia in Parkinson's disease: flow-mediated dilation study.
Identifieur interne : 000591 ( Main/Exploration ); précédent : 000590; suivant : 000592Endothelial dysfunction and hyperhomocysteinemia in Parkinson's disease: flow-mediated dilation study.
Auteurs : Jung Han Yoon [Corée du Sud] ; Jin Soo Lee ; Seok Woo Yong ; Ji Man Hong ; Phil Hyu LeeSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2014.
English descriptors
- KwdEn :
- Aged, Antiparkinson Agents (therapeutic use), Brachial Artery (drug effects), Brachial Artery (physiopathology), Catechols (therapeutic use), Dilatation, Endothelium (drug effects), Endothelium (pathology), Female, Homocysteine (blood), Humans, Hyperhomocysteinemia (diagnosis), Hyperhomocysteinemia (etiology), Levodopa (therapeutic use), Logistic Models, Male, Middle Aged, Nitriles (therapeutic use), Parkinson Disease (blood), Parkinson Disease (complications), Parkinson Disease (pathology), Statistics, Nonparametric.
- MESH :
- chemical , blood : Homocysteine.
- chemical , therapeutic use : Antiparkinson Agents, Catechols, Levodopa, Nitriles.
- blood : Parkinson Disease.
- complications : Parkinson Disease.
- diagnosis : Hyperhomocysteinemia.
- drug effects : Brachial Artery, Endothelium.
- etiology : Hyperhomocysteinemia.
- pathology : Endothelium, Parkinson Disease.
- physiopathology : Brachial Artery.
- Aged, Dilatation, Female, Humans, Logistic Models, Male, Middle Aged, Statistics, Nonparametric.
Abstract
Levodopa (l-dopa) therapy in Parkinson's disease (PD) increases serum homocysteine levels because of its metabolism via catechol O-methyltransferase, which may lead to endothelial dysfunction.
DOI: 10.1002/mds.26005
PubMed: 25154960
Affiliations:
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Le document en format XML
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first="Ji Man" last="Hong">Ji Man Hong</name></author><author><name sortKey="Lee, Phil Hyu" sort="Lee, Phil Hyu" uniqKey="Lee P" first="Phil Hyu" last="Lee">Phil Hyu Lee</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:25154960</idno><idno type="pmid">25154960</idno><idno type="doi">10.1002/mds.26005</idno><idno type="wicri:Area/PubMed/Corpus">000412</idno><idno type="wicri:Area/PubMed/Curation">000412</idno><idno type="wicri:Area/PubMed/Checkpoint">000606</idno><idno type="wicri:Area/Ncbi/Merge">004091</idno><idno type="wicri:Area/Ncbi/Curation">004091</idno><idno type="wicri:Area/Ncbi/Checkpoint">004091</idno><idno type="wicri:Area/Main/Merge">000591</idno><idno type="wicri:Area/Main/Curation">000591</idno><idno type="wicri:Area/Main/Exploration">000591</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Endothelial dysfunction and hyperhomocysteinemia in Parkinson's 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first="Phil Hyu" last="Lee">Phil Hyu Lee</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Antiparkinson Agents (therapeutic use)</term><term>Brachial Artery (drug effects)</term><term>Brachial Artery (physiopathology)</term><term>Catechols (therapeutic use)</term><term>Dilatation</term><term>Endothelium (drug effects)</term><term>Endothelium (pathology)</term><term>Female</term><term>Homocysteine (blood)</term><term>Humans</term><term>Hyperhomocysteinemia (diagnosis)</term><term>Hyperhomocysteinemia (etiology)</term><term>Levodopa (therapeutic use)</term><term>Logistic Models</term><term>Male</term><term>Middle Aged</term><term>Nitriles (therapeutic use)</term><term>Parkinson Disease (blood)</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (pathology)</term><term>Statistics, Nonparametric</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Homocysteine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term><term>Catechols</term><term>Levodopa</term><term>Nitriles</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hyperhomocysteinemia</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Brachial Artery</term><term>Endothelium</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Hyperhomocysteinemia</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Endothelium</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brachial Artery</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Dilatation</term><term>Female</term><term>Humans</term><term>Logistic Models</term><term>Male</term><term>Middle Aged</term><term>Statistics, Nonparametric</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Levodopa (l-dopa) therapy in Parkinson's disease (PD) increases serum homocysteine levels because of its metabolism via catechol O-methyltransferase, which may lead to endothelial dysfunction.</div></front></TEI><affiliations><list><country><li>Corée du Sud</li></country></list><tree><noCountry><name sortKey="Hong, Ji Man" sort="Hong, Ji Man" uniqKey="Hong J" first="Ji Man" last="Hong">Ji Man Hong</name><name sortKey="Lee, Jin Soo" sort="Lee, Jin Soo" uniqKey="Lee J" first="Jin Soo" last="Lee">Jin Soo Lee</name><name sortKey="Lee, Phil Hyu" sort="Lee, Phil Hyu" uniqKey="Lee P" first="Phil Hyu" last="Lee">Phil Hyu Lee</name><name sortKey="Yong, Seok Woo" sort="Yong, Seok Woo" uniqKey="Yong S" first="Seok Woo" last="Yong">Seok Woo Yong</name></noCountry><country name="Corée du Sud"><noRegion><name sortKey="Yoon, Jung Han" sort="Yoon, Jung Han" uniqKey="Yoon J" first="Jung Han" last="Yoon">Jung Han Yoon</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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